Division of Research Spotlight
The Kaiser Permanente Division of Research conducts, publishes, and disseminates epidemiologic and health services research to improve the health and medical care of Kaiser Permanente members and society at large. We seek to understand the determinants of illness and well-being, and to improve the quality and cost-effectiveness of health care. Currently, DOR’s 550-plus staff is working on more than 350 epidemiological and health services research projects.
In the years after the U.S. Preventive Services Task Force recommended against PSA-based screening in all men, many fewer men were diagnosed with prostate cancer but more were found to have advanced cancers, according to a large Kaiser Permanente study published today in the Journal of General Internal Medicine.
Women with greater adiposity, or body fatness, were significantly less likely to receive all of the recommended chemotherapy dose to treat their breast cancer, and they were subsequently 30% more likely to die from the disease as a result, according to research published in JAMA Oncology.
5 Questions for…Dr. Michael A. Bookman, co-leader of a clinical trial that could provide an important new treatment option for women with advanced gynecological cancers.
Despite a broad campaign among physician groups to reduce the amount of imaging in medicine, the rates of use of CT, MRI and other scans have continued to increase in both the United States and Ontario, Canada, according to a new study of more than 135 million imaging exams.
A study in Annals of Surgical Oncology finds that the rate of home recovery after mastectomy increased from 23% regionwide to 61% in the 6 months after the program started, with no significant changes in emergency-department visits, reoperations, or readmissions.
Body composition, especially excess central adiposity or intra-abdominal fat, can result in an increased risk of cardiovascular disease in normal-weight breast cancer survivors, a large new Kaiser Permanente study shows.
A large, multicenter study of advanced medical imaging in pregnancy, published in JAMA Network Open and co-led by Marilyn Kwan, PhD, found that CT scans were performed in 0.8% of pregnancies in the United States and 0.4% in Ontario in 2016; these rates increased nearly fourfold in the United States and doubled in Ontario over the 21 years.
“This study demonstrates the importance at every BMI level of having more precise measures of muscle and fat to help identify those patients who are at high risk of developing cardiovascular disease,” said co-author Bette J. Caan, DrPH.
Coinciding with Colon Cancer Awareness Month (March), Kaiser Permanente Northern California received the National Colorectal Cancer Roundtable’s prestigious “80% by 2018” National Achievement Award, in recognition of screening rates over 83 percent for colorectal cancer.
Does weight gain — or loss — change a breast cancer patient's cancer outcome? What about muscle mass? Epidemiologist Bette Caan wanted to find out about that, and more.